故事
睡不够的时候,还练不练
睡眠不足先拖累技巧和耐力,最大力量受影响较小,同样的强度也会觉得更累。这里讲没睡够那天怎么降档,以及长期睡不够时怎么动。
最后更新:
先读这一段 睡眠不足不会把每种能力压低同样多:最先掉的是需要专注和精准的技巧,最大力量掉得最少。
科普内容,不替代医师诊断或处方;有症状或在服药请咨询医师。
故事路径
第 1 章
少睡先拖累哪些能力
What short sleep costs first
睡眠不足不会把每种能力压低同样多:最先掉的是需要专注和精准的技巧,最大力量掉得最少。 一项汇总 69 篇研究的 里,在 24 小时内只睡了 6 小时或更少之后,投篮、发球这类技巧动作平均变差 20.9%,耐力变差 5.55%,最大力量只降了 2.85%。作者的解释是技巧动作对大脑的要求最高,而反应、注意力和判断正是少睡最先拖累的(见 通宵)。
这一篇写给偶尔一晚没睡好的人,也写给夜里要起来喂奶、上夜班、几周几个月都睡不够的人:今天还练不练,练多狠,长期睡不够时怎么动。
今天可以开始的一步:没睡够的那天,先把需要精准和反应的项目往后放。
两条安全线放在最前面:通宵之后别开车,困得眼皮发沉时也别自己开车去训练;训练中或训练后突发胸痛、胸闷,或在运动中晕倒,立即拨打急救电话,详见长期睡不够时怎么动一章。
这一篇写给偶尔一晚没睡好的人,也写给夜里要起来喂奶、上夜班、几周几个月都睡不够的人:今天还练不练,练多狠,长期睡不够时怎么动。
今天可以开始的一步:没睡够的那天,先把需要精准和反应的项目往后放。
两条安全线放在最前面:通宵之后别开车,困得眼皮发沉时也别自己开车去训练;训练中或训练后突发胸痛、胸闷,或在运动中晕倒,立即拨打急救电话,详见长期睡不够时怎么动一章。
证据 · 哪种少睡、什么时间影响最大
Craven 2022 汇总了 69 篇研究、959 名受试者,其中 89% 是男性;少睡的定义是 24 小时内睡 6 小时或更少。总体看,运动表现平均变差 7.56%,每一类都受影响:技巧 20.9%, 6.15%,全力冲刺和跳跃这类短时爆发 6.26%,耐力 5.55%,最大力量 2.85%。少睡的方式也有差别。整夜不睡,或者比平时早起、砍掉后半夜,影响稳定出现;比平时晚睡、起床时间不变,多数项目没测出稳定的影响,只有技巧和耐力例外。在整夜不睡和早起这两种情况下,训练前每多醒 1 小时,表现平均再降约 0.4%。
一天里的时间也有关系:下午和晚上做的项目受影响更一致,上午做的大多没受明显影响。所以作者建议,预料到会少睡又躲不开时,尽量别整夜不睡或被迫早起,训练放在上午。
力量那一头,Knowles 2018 的系统综述(17 项研究,质量被评为中等或偏弱)发现:一晚不睡对最大力量影响不大;连续几晚睡不够,深蹲这类多关节动作的力量才会下降,单关节动作没有。
读准边界:这些研究大多是年轻男性在实验室里少睡一两晚,测的是当场的表现,不是几周后的训练效果,研究之间差异也很大。
第 2 章
同样的强度为什么更累
Why the same effort feels harder
没睡够时,同样的速度、同样的重量会感觉更累,而这份累主要出在感觉上,不在肌肉里。 一项小实验让 8 个人在 36 小时没睡之后,按睡足时同样的强度在跑步机上持续走:心率和耗氧量都没变,主观用力感却明显更高,坚持到力竭的时间平均短了 11%。另一项实验在一晚没睡后测了腿部肌肉和神经的疲劳,和睡足时没有差别,用力感照样更高。
也就是说,身体那台发动机还在,是大脑给同一份用力打了更高的分。醒得越久,大脑里的睡眠压力越高(见 通宵);它具体怎样改写用力感,目前还没测清楚。
今天可以开始的一步:按感觉来定强度,不按平时的配速或重量。用力感本来就跟着状态走,按它来练,那一天的量会自己变小(见 从零开始动起来,不去健身房也能练)。
也就是说,身体那台发动机还在,是大脑给同一份用力打了更高的分。醒得越久,大脑里的睡眠压力越高(见 通宵);它具体怎样改写用力感,目前还没测清楚。
今天可以开始的一步:按感觉来定强度,不按平时的配速或重量。用力感本来就跟着状态走,按它来练,那一天的量会自己变小(见 从零开始动起来,不去健身房也能练)。
证据 · 三项实验各看到了什么
Martin 1981 让 8 个人分别在睡足后和 36 小时没睡后,在跑步机上以约 80% 的强度持续走到力竭。少睡后坚持的时间平均短了 11%,但人和人差别很大:4 个人变化不到 5%,另外 4 个人少了 15% 到 40%。走的过程中心率和耗氧量没变,主观用力感明显更高。作者认为,少睡的心理效应可能是耐受力下降的原因之一。Temesi 2013 让 12 名爱运动的男性一晚不睡,第二天先骑 40 分钟中等强度,再骑到力竭。少睡后中等强度那段的用力感更高,骑到力竭的时间从 1236 秒降到 1137 秒;骑车前的反应时间长了 8%。但腿部肌肉和神经驱动的疲劳指标,两种情况没有差别。作者的结论是,表现下降大概不是肌肉或中枢疲劳造成的。
Oliver 2009 让 11 名男性在 30 小时没睡后,自己定速跑 30 分钟。他们跑的距离比睡足时少(6037 米对 6224 米),心率和用力感却和睡足时差不多。也就是说,用力感一样,跑得更少;作者认为是用力感被改变了。
还有一条线索指向动机:Knowles 2018 写道,少睡对力量的拖累,出现在没有专门提升动机的安排时。
读准边界:三项实验都只有十几个人以内、都是男性或以男性为主,少睡的是一整晚以上。它们说明感觉变了,但大脑里具体是哪一步改写了用力感,还没测出来。
第 3 章
少睡时肌肉和血糖怎么了
Muscle and blood sugar on short sleep
少睡不只让当天练得差,还会让肌肉造蛋白和处理血糖一起变钝;运动是少数被测出能挡住一部分的东西。 一晚不睡之后,饭后肌肉造新蛋白的速度降了 18%,压力激素皮质醇升高,睾酮下降;一晚只睡 4 小时,肝脏和肌肉对胰岛素的反应也会变钝。
连续几晚都短,这些变化会叠在一起。一项实验把 24 名年轻男性分成三组,其中两组连续 5 晚每晚只在床上 4 小时:只少睡的那组,糖耐量变差,肌肉里线粒体产能的能力和造蛋白的速度都下降;同样少睡、但中间做了 3 次的那组,这些变化没有出现。
今天可以开始的一步:睡不够的那几天,别把运动整个停掉,保留一点自己扛得住的活动。
连续几晚都短,这些变化会叠在一起。一项实验把 24 名年轻男性分成三组,其中两组连续 5 晚每晚只在床上 4 小时:只少睡的那组,糖耐量变差,肌肉里线粒体产能的能力和造蛋白的速度都下降;同样少睡、但中间做了 3 次的那组,这些变化没有出现。
今天可以开始的一步:睡不够的那几天,别把运动整个停掉,保留一点自己扛得住的活动。
证据 · 一晚和五晚分别测到什么
Lamon 2021 让 13 名健康年轻人(7 男 6 女)随机交叉地经历一晚不睡和一晚正常睡,第二天下午测饭后的肌肉蛋白合成:不睡后降了 18%,血里的皮质醇高了 21%,睾酮低了 24%;肌肉蛋白分解的标志物没有变化。作者的结论是,一晚不睡就足以让肌肉对合成信号反应变差,这类急性变化可能是长期睡不够伤到代谢和身体成分的前奏。Donga 2010 让 9 名健康成年人只睡一晚 4 小时,第二天用钳夹试验测胰岛素作用:肝脏放出的糖更多,肌肉收的糖更少,维持血糖平稳需要输入的葡萄糖少了约 25%。更早的 Spiegel 1999 让年轻男性连续几晚少睡,也看到糖耐量变差、傍晚的皮质醇升高。
Saner 2021 的 24 名年轻男性分成三组:每晚在床上 8 小时、每晚 4 小时,以及每晚 4 小时加 3 次,各持续 5 晚。只少睡的那组,糖耐量、线粒体功能和肌浆蛋白合成都下降;加了训练的那组没有出现这些变化。
读准边界:这几项研究都很小,受试者都是健康年轻人,在实验室里只测了几天;Saner 2021 的分组不是随机的,用的也是高强度间歇训练。强度低一些的运动有没有同样的作用,没有测过;按机制推,肌肉一收缩就能把运送葡萄糖的通道 挪到细胞表面,不靠胰岛素也能收糖,所以轻一些的活动应该也有一部分作用,这一步没有被直接测过。
spiegel-1999-lancet-sd-glucoserichter-2013-exercise-glut4
误区 · 多练能抵消没睡够吗
怕睡不够会胖、于是练得更狠,这条路的前提不太对。少睡之后,压食欲的瘦素下降、催饿的胃饥饿素上升,人会更饿,尤其想吃高碳水的高热量食物;Spiegel 2004 在 12 名健康年轻男性身上看到了这一点。这是激素在起作用,不是意志力问题。Nedeltcheva 2010 让 10 名超重的成年人节食 14 天,比较每晚睡 8.5 小时和 5.5 小时:两种情况减掉的体重差不多,但睡得短时,减掉的脂肪只有 0.6 公斤,睡足时是 1.4 公斤,丢掉的去脂体重反而更多(2.4 公斤对 1.5 公斤)。
合起来读:在体重这件事里,睡眠本身就是一个变量,少睡会从食欲和减掉的是什么组织两头起作用。这两项研究里都没有运动这一变量,没有试验直接比较过加练和补觉;但疲劳时硬加强度,正好撞上技巧和反应最差的时候(见少睡先拖累哪些能力一章)。
spiegel-2004-aim-sd-leptin-ghrelinnedeltcheva-2010-sleep-adiposity
第 4 章
没睡够那天怎么降档
Scaling down on a short-sleep day
没睡够的那天,先降强度和难度,再决定练多久;需要精准、反应和最大用力的项目先停。 少睡最先拖累的是技巧和反应,而大重量、对抗和技术性强的练习正好最依赖它们。
可以这样调:
照常活动,但换成轻松的版本,比如快走、轻松骑车;还能说完整的句子,就是轻松。接近力竭的大重量、冲个人纪录、对抗比赛和新学的技术动作,挪到睡够的那天。一定要练,尽量放在上午;热身时平常的重量明显吃力,当天就减量(见 训练常见伤)。不为了怕胖而加练:少睡时更饿,是激素在起作用。
通宵之后别开车,下夜班困得眼皮发沉也别自己开车去训练。咖啡和小睡怎么用,见 通宵。
可以这样调:
照常活动,但换成轻松的版本,比如快走、轻松骑车;还能说完整的句子,就是轻松。接近力竭的大重量、冲个人纪录、对抗比赛和新学的技术动作,挪到睡够的那天。一定要练,尽量放在上午;热身时平常的重量明显吃力,当天就减量(见 训练常见伤)。不为了怕胖而加练:少睡时更饿,是激素在起作用。
通宵之后别开车,下夜班困得眼皮发沉也别自己开车去训练。咖啡和小睡怎么用,见 通宵。
实操 · 今天练不练,怎么判断
先问昨晚是怎么少睡的。按 Craven 2022 的汇总,整夜不睡和比平时早起、砍掉后半夜,对第二天表现的影响最稳定;比平时晚睡、起床时间不变,多数项目影响不明显,只有技巧和耐力例外。醒着的时间越长,表现也越往下掉,所以一定要练的话,上午比傍晚划算。再问今天原本要练什么。轻松的有氧、活动度练习可以照做,用说话测试来管强度:还能比较舒服地一句句说话,强度在通气阈以下。按感觉来练,那一天的量会自己变小,这正是少睡时想要的(见同样的强度为什么更累一章)。需要技巧、反应或接近极限的那部分,挪到睡够的那天。
最大力量在一晚少睡后变化不大,但连续几晚之后,深蹲这类多关节动作的力量会下降(Knowles 2018)。所以连着几天睡不够时,大重量那一天更该往后挪。热身时平常的重量明显吃力就减量,这是教练常用的判断,不是试验得出的切点。
美国运动医学会的立场声明写道,运动方案要按一个人的健康状况和对运动的反应来调整。没睡够,就是这种要往下调的状态之一。
garber-2011-acsm-exercise
背景 · 少睡和受伤有关吗
这件事目前只有观察性的线索。Milewski 2014 调查了一所中学的 112 名运动员(平均 15 岁),把他们自报的睡眠和学校记录里的受伤情况对上:平均每晚睡不到 8 小时的人,受过伤的可能性是睡够 8 小时的人的 1.7 倍(95% 1.0–3.0,区间下限贴着 1)。这是回顾性的关联,睡眠是自报的,不能证明是少睡造成了受伤:训练更多、课业更重的学生,可能同时睡得少、受伤多。按机制推,少睡时反应和技巧先变差,在对抗和复杂动作里更容易出错,这讲得通,但这项研究证明不了。
所以它只是另一个理由,支持没睡够那天先停掉对抗和技术动作,不是说睡少一点就一定会受伤。
milewski-2014-sleep-sports-injury-adolescents
第 5 章
长期睡不够时怎么动
Moving through weeks of short sleep
先记住什么时候必须停。 训练中或训练后突发胸痛、胸闷,或在运动中晕倒,立即拨打急救电话;运动中明显气短、心慌或快要晕倒,立刻停下,不要硬撑,症状不退立即就医。白天困到开车都会打盹的,先别开车,尽快去做睡眠检查(见 睡眠呼吸暂停)。生完孩子后,有伤害自己或宝宝的念头,立即求助:在中国大陆可以拨打全国统一心理援助热线 12356,或者直接去急诊。
除此之外,几周几个月都睡不够时,运动是保住身体的底线,不是又一件要硬撑的任务。规律运动对睡眠本身也有小到中等的好处。
今天可以开始的一步:每天保留一段轻松的活动,比如推着宝宝在外面走一走。产后怎么一步步回到训练,见 怀孕 + 运动;夜班的人,光该在什么时候见、什么时候挡,见 倒班。
除此之外,几周几个月都睡不够时,运动是保住身体的底线,不是又一件要硬撑的任务。规律运动对睡眠本身也有小到中等的好处。
今天可以开始的一步:每天保留一段轻松的活动,比如推着宝宝在外面走一走。产后怎么一步步回到训练,见 怀孕 + 运动;夜班的人,光该在什么时候见、什么时候挡,见 倒班。
机制 · 长期少睡时运动保住了什么
前面几章讲了少睡怎样拖累肌肉和血糖,也讲了有一项实验看到运动挡住了其中一部分(见少睡时肌肉和血糖怎么了一章)。长期睡不够时,这一点更有分量:几周累下来的不是某一天练得差,而是身体处理糖和保住肌肉的能力一直被往下压。运动还会反过来帮睡眠。Kredlow 2015 汇总了 66 项研究:规律运动对总睡眠时长和睡眠效率有小的好处,对入睡快慢有小到中等的好处,对睡眠质量有中等的好处。好处不大,但方向是对的,而且不用花钱。
光是另一条线。眼睛接收到的光,经视网膜传到下丘脑的主时钟(),让它对准一天 24 小时;光照也被用作改善睡眠和情绪的一种手段。白天在户外走一走,同时给了身体活动和光。但对上夜班的人,下班路上的晨光会把时钟往错的方向推,规则正好相反,细节见 倒班。
blume-2019-light-circadian-review
实操 · 新手爸妈和夜班的人怎么动
夜里要起来喂奶的人:一项给 50 名妈妈戴腕表测睡眠的研究里,产后第 2 到 16 周,每晚总睡眠平均约 7.2 小时,看着不少,却被频繁打断;睡眠效率从第 2 周的约 80% 到第 16 周才回到约 90%。所以难的往往不是睡得短,而是睡得碎。这几个月不需要硬撑着练强度,短时间、轻松、能随时停下的活动最合适。运动对产后的情绪也有帮助。美国妇产科医师学会写道,身体活动可以是预防产后抑郁的重要因素。Poyatos-León 2017 汇总了 12 项对照试验:孕期和产后运动让产后抑郁症状下降,幅度中等偏小,本来就有抑郁症状的妈妈下降得更多。产后什么时候、怎样回到训练,要先过产后复查,见 怀孕 + 运动。
上夜班的人:Craven 2022 看到,醒着的时间越长,表现越往下掉。按这个规律推,下了夜班熬着不睡去练,正是醒得最久、表现最差的时候;把运动放在睡过一觉之后更合理。这一步没有在夜班工人身上直接测过。下班后怕胖,答案多半在睡眠和吃饭时间上,不在加练(见 倒班)。
montgomery-downs-2010-postpartum-sleepacog-2020-exercise-pregnancypoyatos-leon-2017-exercise-postpartum-depression
红旗 · 哪些情况要停下就医
下面这些不是没睡够的普通疲劳,而是要立即处理的信号。本站不诊断,出现时先停下来。训练中或训练后突发胸痛、胸闷,像被压住或攥紧,可能放射到手臂、脖子或下颌,伴气短、出冷汗:可能是心脏急症,立即拨打急救电话。在运动中晕倒:立即拨打急救电话。平时晕倒过一次,也要找医生查原因。运动中出现明显气短、心慌或快要晕倒:立刻停下,不要硬撑;症状不退,立即就医。开车去训练或下夜班开车回家时犯困:通宵之后别开车,路上一出现眼皮发沉就马上停车。连续清醒 24 小时的表现,相当于血液酒精浓度 0.10% 时的水平,而微睡眠来的时候,你自己察觉不到。睡的时间不短却总也睡不解乏,或者打鼾很响、白天困到坐下就睡着:可能是。白天困到开车都会打盹的,先别开车,尽快去做睡眠检查(见 睡眠呼吸暂停)。生完孩子后,低落超过两周还没好,或者产后一年内任何时候出现持续低落、提不起兴趣、和宝宝亲近不起来,可能是产后抑郁,要找医生。有伤害自己或宝宝的念头,立即求助:在中国大陆可以拨打全国统一心理援助热线 12356,或者直接去急诊(见 产后恢复与哺乳)。
nhs-postnatal-depression
参考文献 · 16
- Craven, J., McCartney, D., Desbrow, B., Sabapathy, S., Bellinger, P., Roberts, L., & Irwin, C. (2022). Effects of acute sleep loss on physical performance: a systematic and meta-analytical review. Sports Medicine, 52(11), 2669-2690. 69 publications, 227 outcome measures, 959 participants (89% male); sleep loss defined as 6 h or less in 24 h. Overall performance change -7.56% (95% CI -11.9 to -3.13), significant for every exercise category: skill -20.9% (9 studies; tasks with a high cognitive component such as tennis serving or free-throw shooting), high-intensity interval exercise -6.15%, anaerobic power -6.26%, endurance -5.55%, speed/power endurance -2.90%, strength -2.85% (full text, Table 2). 'Consistent negative effects only observed with deprivation and late-restriction protocols' (late restriction = waking earlier than normal; early restriction = going to sleep later); the discussion adds that early restriction produced no change in performance 'except for skill and endurance tasks'; '~0.4% decrease for every hour awake prior to exercise' for deprivation and late restriction; 'The negative effects of sleep loss on different exercise tasks performed in the PM were consistent, while tasks performed in the AM were largely unaffected.' The authors attribute the larger skill effect to 'the higher cognitive demand' of those tasks (a proposed explanation). Conclusion: 'Sleep loss appears to have a negative impact on exercise performance. If sleep loss is anticipated and unavoidable, individuals should avoid situations that lead to experiencing deprivation or late restriction, and prioritise morning exercise in an effort to maintain performance' (abstract, PMID 35708888; full text, PMC9584849). 10.1007/s40279-022-01706-y
- Knowles, O. E., Drinkwater, E. J., Urwin, C. S., Lamon, S., & Aisbett, B. (2018). Inadequate sleep and muscle strength: implications for resistance training. Journal of Science and Medicine in Sport, 21(9), 959–968. 10.1016/j.jsams.2018.01.012
- Dawson, D., & Reid, K. (1997). Fatigue, alcohol and performance impairment. Nature, 388(6639), 235. 10.1038/40775
- NHS. (2026). Heart attack: symptoms. Symptoms can include chest pain that may feel like crushing or squeezing on the chest and may spread to the arm, neck and jaw; feeling short of breath; feeling or being sick; feeling like indigestion; sweating; and pale, blue or grey skin. Call 999 for chest pain that feels tight or like squeezing, or that spreads to the arms, neck or jaw, with severe difficulty breathing, or if someone becomes unresponsive. A heart attack needs emergency treatment in hospital (page last reviewed 31 March 2026). www.nhs.uk/conditions/heart-attack/symptoms
- NHS. (2026). Fainting (page last reviewed 17 August 2026). Fainting is when you pass out for a short time; it is not usually serious, but anyone who has fainted should see a GP to find out what might have caused it. Causes can include standing up too quickly (which could be a sign of low blood pressure), not eating or drinking enough, being too hot, being very upset or in severe pain, heart problems, and taking drugs or drinking too much alcohol. Call 999 if someone is not breathing, cannot be woken up within 1 minute, has not fully recovered or has difficulty with speech or movement, has chest pain or a pounding, fluttering or irregular heartbeat (palpitations), has seriously hurt themselves before or after fainting, is shaking or jerking (a seizure), fainted while exercising, or fainted while lying down; do not drive yourself to A&E. If you feel about to faint: lie down with your legs raised, or if you cannot, sit with your head lowered between your knees; drink some water; cross your legs while standing up or rock up and down on your toes; clench your fists. If you see someone faint: check whether they respond by gently shaking their shoulders and asking loudly; if not, shout for help and tilt back the head and lift the chin; listen for breathing for at least 10 seconds; if they are breathing normally, lay them on their back and raise their legs (on their side if pregnant, especially over 28 weeks); they usually wake up within 30 seconds. www.nhs.uk/conditions/fainting
- Martin, B. J. (1981). Effect of sleep deprivation on tolerance of prolonged exercise. European Journal of Applied Physiology and Occupational Physiology, 47(4), 345-354. Eight subjects walked on a treadmill at about 80% of VO2max after normal sleep and after 36 h without sleep. Sleep loss reduced work time to exhaustion by an average of 11%; four subjects changed by less than 5% and four lost 15% to 40%. 'During the walk, sleep loss resulted in significantly greater perceived exertion (p less than 0.05), even though exercise heart rate and metabolic rate (VO2 and VCO2) were unchanged.' Conclusion: 'These findings suggest that the psychological effects of acute sleep loss may contribute to decreased tolerance of prolonged heavy exercise' (abstract, PMID 7199438). 10.1007/BF02332962
- Temesi, J., Arnal, P. J., Davranche, K., Bonnefoy, R., Levy, P., Verges, S., & Millet, G. Y. (2013). Does central fatigue explain reduced cycling after complete sleep deprivation? Medicine & Science in Sports & Exercise, 45(12), 2243-2253. Twelve active males, one night of complete sleep deprivation versus normal sleep. After sleep deprivation, time to task failure was shorter (1137 vs 1236 s) and perceived exertion during 40 min of submaximal cycling was greater; mean reaction time was 8% longer before cycling; no other differences in neuromuscular function or cognitive control were observed between conditions, and acute submaximal exercise counteracted the cognitive deterioration. Conclusion: one night of complete sleep deprivation 'resulted in decreased time to task failure and cognitive performance and higher RPE compared with the control condition. The lack of difference in neuromuscular function between CO and SD indicates that decreased SD exercise performance was probably not caused by increased muscular or central fatigue' (abstract, PMID 23760468). 10.1249/MSS.0b013e31829ce379
- Oliver, S. J., Costa, R. J., Laing, S. J., Bilzon, J. L., & Walsh, N. P. (2009). One night of sleep deprivation decreases treadmill endurance performance. European Journal of Applied Physiology, 107(2), 155-161. Eleven males, two randomised trials: after normal sleep and after 30 h without sleep, a 30-min pre-load at 60% VO2max then a 30-min self-paced treadmill distance test. Less distance was covered after sleep deprivation (6037 vs 6224 m); cardio-respiratory parameters, RPE and speed did not differ during the pre-load or distance test (mean RPE 14.8 vs 14.9). Conclusion: 'one night of sleep deprivation decreased endurance performance with limited effect on pacing, cardio-respiratory or thermoregulatory function. Despite running less distance after sleep deprivation compared with control, participants' perception of effort was similar indicating that altered perception of effort may account for decreased endurance performance after a night without sleep' (abstract, PMID 19543909). 10.1007/s00421-009-1103-9
- Lamon, S., Morabito, A., Arentson-Lantz, E., Knowles, O., Vincent, G. E., Condo, D., Alexander, S. E., Garnham, A., Paddon-Jones, D., & Aisbett, B. (2021). The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment. Physiological Reports, 9(1), e14660. Randomized crossover in 13 healthy young adults (seven male, six female): one night of total sleep deprivation versus normal sleep. 'Acute sleep deprivation reduced muscle protein synthesis by 18%' (postprandial fractional synthesis rate, measured 13:00-15:00); plasma cortisol rose 21% and plasma testosterone fell 24%; no difference was found in markers of protein degradation. Conclusion: 'A single night of total sleep deprivation is sufficient to induce anabolic resistance and a procatabolic environment. These acute changes may represent mechanistic precursors driving the metabolic dysfunction and body composition changes associated with chronic sleep deprivation' (abstract, PMID 33400856). 10.14814/phy2.14660
- Donga, E., van Dijk, M., van Dijk, J. G., Biermasz, N. R., Lammers, G. J., van Kralingen, K. W., Corssmit, E. P. M., & Romijn, J. A. (2010). A single night of partial sleep deprivation induces insulin resistance in multiple metabolic pathways in healthy subjects. The Journal of Clinical Endocrinology & Metabolism, 95(6), 2963–2968. 9 healthy adults (5 men, 4 women), crossover: a normal night vs one night of 4 h sleep (226 vs 454 min). Hyperinsulinaemic clamp next day: endogenous glucose production higher (hepatic insulin resistance), glucose disposal lower (32.5 vs 40.7), glucose infusion rate about 25% lower (abstract, PMID 20371664). 10.1210/jc.2009-2430
- Saner, N. J., Lee, M. J., Kuang, J., Pitchford, N. W., Roach, G. D., Garnham, A., Genders, A. J., Stokes, T., Schroder, E. A., Huo, Z., Esser, K. A., Phillips, S. M., Bishop, D. J., & Bartlett, J. D. (2021). Exercise mitigates sleep-loss-induced changes in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and diurnal rhythms. Molecular Metabolism, 43, 101110. 24 healthy young males allocated (to minimise baseline differences, not randomly) to Normal Sleep (8 h in bed for five nights), Sleep Restriction (4 h in bed for five nights) or Sleep Restriction plus three sessions of high-intensity interval exercise. The sleep-restriction group had reduced glucose tolerance, reduced mitochondrial respiratory function, a lower rate of sarcoplasmic protein synthesis and reduced amplitude of diurnal rhythms; 'These effects were not observed when incorporating three sessions of HIIE during this period.' Conclusion: 'A five-night period of sleep restriction leads to reductions in mitochondrial respiratory function, SarcPS, and amplitude of skin temperature diurnal rhythms, with a concurrent reduction in glucose tolerance. We provide novel data demonstrating that these same detrimental effects are not observed when HIIE is performed during the period of sleep restriction' (abstract, PMID 33137489). 10.1016/j.molmet.2020.101110
- Reed, J. L., & Pipe, A. L. (2014). The talk test: a useful tool for prescribing and monitoring exercise intensity. Current Opinion in Cardiology, 29(5), 475-480. 'In healthy adults and patients with cardiovascular disease, comfortable speech is likely possible (equivocal or last positive talk test stage) when exercise intensity is below the ventilatory or lactate threshold, and not likely possible (negative talk test stage) when exercise intensity exceeds the ventilatory or lactate threshold.' The talk test has been consistent across walking, jogging, cycling, elliptical trainer and stair stepper, and may not be practical for high-intensity interval training. Summary: it 'is a valid, reliable, practical and inexpensive tool for prescribing and monitoring exercise intensity in competitive athletes, healthy active adults and patients with cardiovascular disease' (abstract, PMID 25010379). 10.1097/HCO.0000000000000097
- Tefft, B. C. (2016). Acute sleep deprivation and risk of motor vehicle crash involvement. AAA Foundation for Traffic Safety Research Brief. aaafoundation.org/acute-sleep-deprivation-risk-motor-vehicle-crash-involvement
- Chung, F., Yegneswaran, B., Liao, P., Chung, S. A., Vairavanathan, S., Islam, S., Khajehdehi, A., & Shapiro, C. M. (2008). STOP questionnaire: a tool to screen patients for obstructive sleep apnea. Anesthesiology, 108(5), 812-821. 10.1097/ALN.0b013e31816d83e4
- Centers for Disease Control and Prevention. (2024). Urgent maternal warning signs (Hear Her campaign; last updated May 15, 2024). Be aware of urgent maternal warning signs during pregnancy and in the year after delivery, and seek medical care immediately for: a headache that won't go away or gets worse; dizziness or fainting; changes in vision; fever of 100.4°F or higher; extreme swelling of the hands or face; thoughts about harming yourself or your baby; trouble breathing; chest pain or fast-beating heart; severe nausea and throwing up; severe belly pain that doesn't go away; vaginal bleeding or discharge after pregnancy; severe swelling, redness or pain of a leg or arm. Tell providers if you were pregnant within the last year. www.cdc.gov/hearher/maternal-warning-signs/index.html
- Kredlow, M. A., Capozzoli, M. C., Hearon, B. A., Calkins, A. W., & Otto, M. W. (2015). The effects of physical activity on sleep: A meta-analytic review. Journal of Behavioral Medicine, 38(3), 427-449. Acute exercise → small improvements in sleep onset latency and total sleep time; chronic regular exercise → larger effects (latency ↓ ~13 min). Late-evening high-intensity work disrupts sleep. 10.1007/s10865-015-9617-6