营销话术证据 B · meta 分析
更年期靠补剂搞定
真相
更年期激素治疗能同时作用于骨密度、潮热盗汗和阴道萎缩；植物雌激素效果零散，替代不了它。
机制速览
很多女性 40 多岁开始注意到：月经变得没规律，动不动一阵燥热出汗，晚上睡得浅，情绪和记忆也不太稳。这多半不是哪里坏了，而是身体进入了一个叫围绝经期的过渡阶段：卵巢分泌的雌激素在收尾，而且不是平稳地减少，是忽高忽低。
来源（2）
- Harlow, S. D., Gass, M., Hall, J. E., Lobo, R., Maki, P., Rebar, R. W., Sherman, S., Sluss, P. M., & de Villiers, T. J. (2012). Executive summary of the Stages of Reproductive Aging Workshop +10: addressing the unfinished agenda of staging reproductive aging. The Journal of Clinical Endocrinology & Metabolism, 97(4), 1159-1168.
- The 2022 Hormone Therapy Position Statement of The North American Menopause Society Advisory Panel. (2022). The 2022 hormone therapy position statement of The North American Menopause Society. Menopause, 29(7), 767-794. Hormone therapy remains the most effective treatment for vasomotor symptoms and the genitourinary syndrome of menopause and has been shown to prevent bone loss and fracture; treatment should be individualised and periodically re-evaluated; for women younger than 60 or within 10 years of menopause onset without contraindications, the benefit-risk ratio is favourable for bothersome vasomotor symptoms and prevention of bone loss (abstract, PMID 35797481).