营销话术证据 B · meta 分析
PCOS 限糖治本
真相
多囊卵巢综合征的核心是胰岛素抵抗和雄激素两条线；只限糖只动了一条，真正的杠杆是减重 5-10%，再加肌醇（myo-inositol）。
机制速览
多囊卵巢综合征（PCOS）是育龄女性最常见的内分泌问题之一。名字里带着卵巢，但它牵动的远不止卵巢：月经和排卵被打乱，雄激素偏高带来长痘和多毛，体重、血糖和怀孕都可能受影响。超声上那些小卵泡，只是它最容易被看到的一个表现。
来源（2）
- Teede, H. J., Tay, C. T., Laven, J. J. E., et al. (2023). Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. Fertility and Sterility, 120(4), 767-793. 254 recommendations and practice points. The full text (the simultaneous JCEM publication, PMC10505534) states: PCOS prevalence 10% to 13% (Rotterdam criteria); follicle number per ovary >= 20 in at least 1 ovary is the adult PCOM threshold; AMH may replace ultrasound in adults only; insulin resistance is a pathophysiological factor, but clinically available insulin assays are of limited clinical relevance and should not be used in routine care; inositol could be considered for metabolic measures with limited clinical benefit, metformin should be considered over inositol for hirsutism and central adiposity, and inositol for infertility should be considered experimental (abstract, PMID 37589624; full text, PMC10505534).
- Rosenfield, R. L., & Ehrmann, D. A. (2016). The pathogenesis of polycystic ovary syndrome (PCOS): the hypothesis of PCOS as functional ovarian hyperandrogenism revisited. Endocrine Reviews, 37(5), 467-520.