营销话术证据 B · meta 分析
能量饮料 + 咖啡更猛
真相
300-400 mg 咖啡因加上糖、牛磺酸和瓜拉那：美国食药监局的不良事件系统记录过与之相关的急性心律失常和高血压事件。
机制速览
你不困，不是因为血里咖啡因高，而是因为腺苷被挡住了。
来源（2）
- Wesensten, N. J., Belenky, G., Kautz, M. A., Thorne, D. R., Reichardt, R. M., & Balkin, T. J. (2002). Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine. Psychopharmacology, 159(3), 238–247.
- EFSA Panel on Dietetic Products, Nutrition and Allergies. (2015). Scientific opinion on the safety of caffeine. EFSA Journal, 13(5), 4102. Abstract: single doses up to 200 mg (about 3 mg/kg bw for a 70-kg adult) and habitual intake up to 400 mg per day raise no safety concerns for non-pregnant adults; up to 200 mg per day in pregnancy raises no concern for the fetus; single doses and habitual intake up to 200 mg by lactating women raise no concern for breastfed infants; for children and adolescents the data were insufficient to derive a safe intake, and the Panel suggests the adult 3 mg/kg bw per day as a basis. Typical energy-drink constituents, and alcohol up to about 0.65 g/kg bw, would not affect the safety of single caffeine doses up to 200 mg (abstract, Wiley page via Wayback snapshot 8 January 2025).