Urolithin A

尿石素 A · 菌把石榴变成线粒体标签

Place · Level 3 · Supplements

Connected to · 2

synergy · 1

Gut Microbiome
Ellagitannins become urolithin A only through some gut microbes; without that community, pomegranate does not make the molecule.

contrast · 1

NMN / NR
NMN/NR tops up the NAD cofactor pool; urolithin A takes broken mitochondria apart by mitophagy. Two anti-aging tracks, not the same road.

石榴自己没有这个分子

Stop 1/4

Pomegranate does not contain this molecule

Pomegranate, walnuts and berries hold ellagitannins. After you eat them, some gut microbes have to take them apart into urolithin A. The fruit does not already contain the finished molecule. Ryu 2016 writes UA as a natural compound that induces mitophagy after oral intake: in C. elegans it limited age-related piles of dysfunctional mitochondria and extended lifespan; in rodents exercise capacity improved.

So shelf copy that pomegranate anti-ages you skips the microbes in the middle. Without that community the same fruit does not make this molecule. The microbiome island covers the community. This island follows one metabolite.

Read story

Educational content, not medical advice — consult a clinician.

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Urolithin A

尿石素 A · 菌把石榴变成线粒体标签

Place · Level 3 · Supplements

Connected to · 2

synergy · 1

Gut Microbiome
Ellagitannins become urolithin A only through some gut microbes; without that community, pomegranate does not make the molecule.

contrast · 1

NMN / NR
NMN/NR tops up the NAD cofactor pool; urolithin A takes broken mitochondria apart by mitophagy. Two anti-aging tracks, not the same road.

石榴自己没有这个分子

Stop 1/4

Pomegranate does not contain this molecule

Pomegranate, walnuts and berries hold ellagitannins. After you eat them, some gut microbes have to take them apart into urolithin A. The fruit does not already contain the finished molecule. Ryu 2016 writes UA as a natural compound that induces mitophagy after oral intake: in C. elegans it limited age-related piles of dysfunctional mitochondria and extended lifespan; in rodents exercise capacity improved.

So shelf copy that pomegranate anti-ages you skips the microbes in the middle. Without that community the same fruit does not make this molecule. The microbiome island covers the community. This island follows one metabolite.

Read story

Educational content, not medical advice — consult a clinician.