The claimEvidence C · limited
α-GPC / CDP-choline = nootropic for healthy adults
The evidence
A single dose shows no reliable thinking or memory benefit in healthy adults; long-term human data is thin.
The mechanism, in brief
α-GPC and CDP-choline (citicoline) are two choline supplements sold for the brain. Think of them as brain-bound versions of ordinary choline, pitched as better at getting into the brain. In Europe and Japan they are prescription drugs, given to people with dementia or with cognitive decline after a stroke; in the US…
Sources (1)
- Alvarez-Sabín, J., & Román, G. C. (2011). Citicoline in vascular cognitive impairment and vascular dementia after stroke. Stroke, 42(1 Suppl), S40-S43.