A CLOSER LOOK
Capsaicin opens a pain-alarm channel
Molecule and channel are functional symbols; the final node is a heat signal, not rising mouth temperature or an actual burn.
- 1TRPV1 opens
- Capsaicin activates a channel that also senses heat and acid, allowing calcium and sodium into the nerve ending.
- 2It follows the pain pathway
- Nerves send an alarm that feels hot, through a route different from the taste buds' five tastes.
Illustration for understanding; not to scale. Saved figures include explanations and sources.