Place · Level 3
视网膜的光开关 · 上皮屏障的维护者 · 免疫成熟的分化信号
cofactor · 2
→Zinc
Zinc is required for hepatic synthesis of retinol-binding protein (RBP4). Zinc deficiency → low RBP4 → vitamin A can't be mobilized even when stores are adequate, mimicking A deficiency. Textbook-level hidden lock.
Vitamin A is the raw material for rhodopsin, so night vision fails first when it runs short. That line governs dark adaptation, not refractive error — marketing routinely conflates the two.
regulates · 1
Vitamin C, E and the carotenoids together form the lung's antioxidant net, but the effect is weak and dietary-pattern-level. The single-nutrient counter-example is hard: beta-carotene raised lung-cancer risk in smokers — the classic case of antioxidising too hard.