Story
cofactor · 1
Keeping joints healthy depends not only on daytime activity but also on repair at night: growth hormone is released mainly during deep sleep. Chronic short sleep cuts deep sleep; how much that affects joint repair has not been measured directly, but the mechanism points the wrong way.
regulates · 1
A joint that suddenly turns red, hot and swollen is a different problem from wear and tear: urate crystals falling into the joint space set off acute inflammation. An attack like this needs a prompt medical visit to tell gout apart from a joint infection.
contrast · 2
Glucosamine and chondroitin generally do no harm, but do not expect them to repair cartilage, and do not put them ahead of exercise and weight loss, which are the core treatments for osteoarthritis with the strongest evidence.
The promise that collagen peptides fix joints goes too far. In a 24-week trial of college athletes with activity-related joint pain, those taking collagen hydrolysate improved more on pain scores, but that is a signal about symptoms, not evidence that cartilage was rebuilt. First-line care for joints is still exercise plus weight loss.