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regulates · 1
Coconut oil is about 82% saturated fat, and its main fatty acid, lauric acid, clearly raises LDL cholesterol: in pooled clinical trials, LDL cholesterol was about 10 mg/dL higher than with unsaturated vegetable oils. In 2017 the American Heart Association (AHA) advised against using it as a healthy oil.
Mechanism · How saturated fat raises LDL
The surface of a liver cell carries LDL receptors, like a row of cranes along a dock: as blood flows past, they hook LDL particles into the cell and take them apart. How many cranes there are is set in reverse by the cell's cholesterol stock: when the stock is ample, the instruction to make receptors is turned down. Saturated fat reaching the liver props that stock up, the cranes thin out, and particles stay in the blood longer. Lauric acid carries the name of a medium-chain fat yet does exactly this. A statin works the other way round: it leaves the liver cell short of cholesterol, the cranes multiply, and particles are cleared from the blood.
Numbers · How much coconut oil raises LDL
Mensink 2016, a synthesis prepared for the World Health Organization, establishes that lauric acid clearly raises LDL cholesterol. Neelakantan 2020 pooled clinical trials comparing coconut oil with unsaturated vegetable oils: LDL cholesterol was about 10 mg/dL higher and HDL cholesterol about 4 mg/dL higher. The AHA's 2017 advisory says coconut oil is about 82% saturated fat, raises LDL cholesterol and has no known favorable effect to offset that, and advises against its use. A rise in HDL at the same time does not carry away the extra LDL particles.
In practice · What it replaces matters
The effect of a spoonful of oil depends on what it replaces: in place of butter it improves little, and in place of olive oil it swaps out unsaturated fat that was doing you good. So coconut oil belongs among the fats to be replaced, not among health products. It is also not medium-chain triglyceride (MCT) oil: true MCT oil is purified C8 and C10 fatty acids that go straight to the liver through the portal vein, while coconut oil's main fat is C12 lauric acid, which is handled more like a long-chain fat. Using it now and then for flavor or baking is fine; making it your everyday cooking oil is the wrong direction.