Polycystic Ovary Syndrome

synergy · 1

• ↔Type 2 Diabetes

  Sex-hormone imbalance amplifies insulin resistance: higher androgens in PCOS worsen it, while resistance itself lowers SHBG and pushes free androgen up — a loop that turns on its own, which is why both sides need managing together.

  REVIEW · AGUIDE · A

regulates · 1

• →Hair Loss

  The androgen excess of PCOS thins scalp follicles while coarsening facial and body hair — one hormone, two opposite-looking outcomes. Hair loss alongside irregular cycles, acne or hirsutism is a reason to check hormones.

  GUIDE · AREVIEW · A

contrast · 3

• ≠Andropause

  One SHBG mechanism, opposite clinical readings by sex: insulin resistance lowers SHBG, which in men looks like low total testosterone with possibly normal free T, and in women raises free T — the route behind the androgen picture in PCOS.

  GUIDE · ACOHORT · B

• ≠Berberine

  Berberine activates AMPK in a direction similar to metformin, which is why it gets offered as a substitute. But its bioavailability is poor and it is contraindicated in pregnancy — which matters especially for PCOS patients whose goal is conception.

  GUIDE · AREVIEW · B

• ≠Chromium

  Chromium is sold as a must-have for blood sugar on the strength of glucose tolerance factor, a concept that has since been overturned. For insulin resistance in PCOS it does not belong in the evidence-backed column.

  GUIDE · AREVIEW · B